Environmental quality standards for diclofenac derived under the European water framework directive: 2. Avian secondary poisoning

نویسندگان

چکیده

Abstract Diclofenac is a nonsteroidal anti-inflammatory human and veterinary medicine widely detected in European surface waters, especially downstream from Wastewater Treatment Plants. With some notable exceptions, uses of diclofenac Europe are greatly restricted, so wastewater the key Europe-wide exposure route for wildlife that may be exposed via aquatic environment. Proposed Environmental Quality Standards (EQS) which include an assessment avian secondary poisoning under consideration by Commission (EC) to support aims Water Framework Directive (WFD). In this paper we summarise information on toxicity plus laboratory field evidence bioaccumulation bioconcentration food items. A safe threshold value birds 3 ?g kg ?1 wet weight was previously derived Medicines Agency should adopted as EQS WFD maintain consistency across regulations. This also consistent with values 1.16–3.99 µg diet proposed EC WFD. Water-based 5.4 or 230 ng L freshwater these dietary standards, respectively, us, large difference caused primarily use different bioaccumulation. simple potential water-based compliance performed both latter against reported concentrations samples collected freshwaters. shows exceedances EC-derived would very widespread while us confined relatively small number sites only Member States. Since there no any declines waterbird populations associated recommend conservative water protect through chain.

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ژورنال

عنوان ژورنال: Environmental Sciences Europe

سال: 2022

ISSN: ['2190-4715', '2190-4707']

DOI: https://doi.org/10.1186/s12302-022-00601-7